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00:00 - Breakthrough Discovery: Ozempic May Reduce Stroke Risk and Improve Recovery 05:22 - GLP-1s Could Protect Against Neurodegeneration, Study Finds 1. Breakthrough Discovery: Ozempic May Reduce Stroke Risk and Improve Recovery Scientists have identified a new health benefit of Ozempic, a medication typically prescribed for type 2 diabetes and obesity. New research reveals that GLP-1 drugs like Ozempic may reduce stroke risk and improve recovery. In this video, we'll explore the findings of three new studies presented at the 22nd Annual Meeting of the Society of NeuroInterventional Surgery (SNIS). We'll discuss how Ozempic may lower the risk of dying from stroke-related causes, reduce the risk of stroke, and improve patient outcomes after brain hemorrhages. Join us as we delve into the potential protection offered by these medications and what this means for the prevention and treatment of stroke and related brain injuries. 2. GLP-1s Could Protect Against Neurodegeneration, Study Finds Recent research indicates that GLP-1 agonists like Novo Nordisk's semaglutide and Eli Lilly's tirzepatide, commonly used for weight loss and diabetes, may lower the risk of developing neurodegenerative disorders such as dementia. This retrospective cohort study, published in JAMA Network Open, analyzed data from over 60,800 adults with type 2 diabetes and obesity. The study found that patients treated with GLP-1 analogs had a 37% lower risk of dementia and significant reductions in the risks of ischemic stroke and all-cause mortality compared to those on other antidiabetic medications. However, the study did not find an association between GLP-1 therapies and Parkinson's disease, mild cognitive impairment, and intracerebral hemorrhage. The potential neuroprotective benefits of GLP-1 drugs are promising, though the study's limitations include potential residual confounding factors and the lack of biomarker and genetic data. Future randomized trials are needed to confirm these findings. Novo Nordisk and Eli Lilly are already conducting Phase III trials to test the effects of GLP-1 agonists on Alzheimer's disease. Stay informed about the latest in medical research and the potential of GLP-1 agonists in neuroprotection.
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