Uncovering a Game-Changing Solution for Weight Loss: Oral Semagulatide (GLP-1 receptor agonist, active substance in currently available injectable Ozempic)
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Novo Nordisk recently announced topline oral semaglutide results. People who received a daily 50-mg dose of oral semaglutide, a glucagon-like peptide-1 receptor agonist, experienced greater #weightloss than those who received a placebo pill, according to results from a 68-week phase 3 clinical trial that included 667 adults with obesity or overweight and 1 or more concurrent conditions. On average, participants experienced a 15.1% decrease in weight after receiving the medication, regardless of treatment adherence, compared with a 2.4% weight loss with the placebo. The amount of weight loss with oral semaglutide was similar to that achieved by people who received a weekly 2.4-mg injected dose of #semaglutide, marketed as Wegovy. Mild or moderate gastrointestinal events were the most common adverse effects
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Conclusion: In adults with overweight or #obesity without type 2 diabetes, #oralsemaglutide 50 mg once per day led to a superior and clinically meaningful decrease in bodyweight compared with placebo.
["Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): a randomised, double-blind, placebo-controlled, phase 3 trial" The Lancet, June 25, 2023]
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Many individuals struggling with obesity are constantly seeking effective ways to lose weight and improve their overall health. One of the most common methods for weight loss is through the use of medications such as semaglutide. Semaglutide is a glucagon-like peptide-1 receptor agonist that has been shown to help individuals lose weight by reducing appetite and calorie intake. Traditionally, semaglutide has been administered through injections. However, a new oral form of semaglutide has recently become available, sparking interest in comparing the effectiveness of oral semaglutide to injections for weight loss.
Oral Semaglutide vs. Injectable Semaglutide
Injectable semaglutide has been widely used for weight loss and has been shown to be effective in helping individuals achieve significant weight loss. The injectable form is typically administered once a week and has been proven to reduce hunger, increase fullness, and lead to sustainable weight loss over time. However, the injections can be inconvenient and uncomfortable for some individuals, which has led to the development of an oral form of semaglutide.
Oral semaglutide offers a more convenient and discreet option for individuals looking to lose weight. The oral form is taken once daily, making it easier to incorporate into daily routines compared to weekly injections. Additionally, oral semaglutide has been shown to be just as effective as injectable semaglutide in promoting weight loss. Studies have found that individuals taking oral semaglutide experienced similar reductions in weight compared to those taking the injectable form.
Benefits of Oral Semaglutide
One of the main benefits of oral semaglutide is its convenience. Because it is taken orally, individuals do not have to worry about the discomfort and inconvenience of injections. This can lead to better adherence to the medication, resulting in more consistent weight loss outcomes. Additionally, oral semaglutide has been shown to have a similar safety profile to the injectable form, with the most common side effects being gastrointestinal symptoms such as nausea and diarrhea.
Another benefit of oral semaglutide is its potential to reach a wider population of individuals struggling with obesity. Some individuals may have a fear of needles or may be unable to administer injections themselves, making the oral form a more attractive option. By offering an oral alternative to injectable semaglutide, more individuals may be willing to try this medication and benefit from its weight loss effects.
Considerations for Choosing Between Oral and Injectable Semaglutide
When considering whether to use oral or injectable semaglutide for weight loss, there are several factors to take into account. Some individuals may prefer the convenience of oral semaglutide and may find it easier to incorporate into their daily routine. Others may prefer the proven track record of injectable semaglutide and be more comfortable with the weekly injections. Ultimately, the choice between oral and injectable semaglutide will depend on individual preferences and needs.
It is important to consult with a healthcare provider before starting any weight loss medication, including semaglutide. A healthcare provider can help determine the best treatment option based on individual health history, weight loss goals, and lifestyle factors. Whether choosing oral or injectable semaglutide, it is essential to follow a comprehensive weight loss plan that includes healthy eating, regular physical activity, and ongoing support from healthcare professionals.
Conclusion
In conclusion, both oral and injectable forms of semaglutide have been shown to be effective in promoting weight loss and improving health outcomes for individuals struggling with obesity. While injectable semaglutide has been the traditional choice for weight loss, oral semaglutide offers a more convenient and discreet option for individuals looking to achieve their weight loss goals. By considering factors such as convenience, efficacy, and individual preferences, individuals can make an informed decision about whether oral or injectable semaglutide is the right choice for their weight loss journey.
30-Minute Workout for Your Complete Body and Heart ❤️
A 30-minute workout is not only beneficial for your entire body but also great for your heart. This routine activates the afterburn effect, enabling your body to burn calories even after you’ve finished working out. Regular cardiovascular exercise strengthens the heart, improves blood circulation, and lowers the risk of heart disease.
➡️ Warm-Up
Start with a quick warm-up to prepare your body for the workout.
🏋️♀️ Workout Routine
1. 30 Seconds Full-Speed Sprint
2. Push-Ups - 12 reps
• For an advanced variation, choose a more challenging type.
3. 30 Seconds Curtsey Lunges - add jumps to make it more exciting
4. Hanging Leg Raises
⏯️ Active Rest
After completing these exercises, go directly to the treadmill for one minute of active rest. Then, start the next round again.
⏯️Format/Challenge 🏆
10 rounds
30 minutes
▶️ Cool Down and Recovery
After finishing your workout, it’s essential to cool down and allow your body to recover. Spend 5-10 minutes doing light stretching and deep breathing exercises to relax your muscles and lower your heart rate gradually. This helps prevent muscle soreness and promotes better recovery.
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How to burn belly fat? What foods should you eat to shed off the excess abdominal fat?
Well, you need a diet plan that includes foods with the right quantity of vitamins and other essential ingredients that’s required to promote the hormones needed to burn fat throughout the body. Outlined in this short video are 8 best foods that burn belly fat.
Grapefruit: Fitness experts has it that incorporating grapefruit in your daily diet can actually fasten your weight loss target, and you don’t really need to make a lot of changes in your diet to achieve that. The high water content of grapefruits help in keeping you hydrated. Also, the fruit contains fat burning enzymes, which makes it a super food for weight loss.
Yogurt: Yogurt is made up four different bioactive compounds that can help you in shedding off the excess belly fat. In addition, its probiotics contents are good for digestion and they help you stay full.
Avocado: You may not know it, but avocado is a truly magic fruit and this is mostly because of their richness in various important nutrients. The presence of monounsaturated fatty acids in this fruit helps in burning of belly fat, plus it’s fiber content helps in keeping hunger at bay.
Cucumber: Cucumber is one of the most refreshing foods and they have low-calorie content as well. One full cucumber contains about 45 calories, making it the perfect food for your stomach. In addition, they contain approximately 96 percent water, thereby making it one of the best cooling foods you can eat to stay healthy.
Lean meats and fish: Perfect examples of these types of foods are tuna, salmon, chicken and turkey, as they are full of omega-3s and as a result can prevent stress chemicals that promote fat abs. Of course, you shouldn’t eat meat if you’re a vegetarian, but if you insist, turkey and chicken are healthier options.
Barley: Another good food to burn belly fat is barley. It’s high fiber and protein content, and low fat content helps in reducing cravings, as well as provide the body with a steady supply of energy.
Pomegranates: Various studies on the health benefits of this fruit has it that its polyphenols antioxidant content helps to increase metabolism and get rid of toxins from the body. In addition, pomegranates help in lowering your appetite. So, it’s ideal to drink a glass of pomegranate juice during breakfast or just add it to your salad bowl before lunch.
Cherries: Eating some tart Montmorency cherries before going to bed is an ideal option because aside from its high melatonin content that can help you sleep well, it’s also a strong antioxidant and can accelerate the burning of belly fat.
If you’ve been looking to shed off that frustrating belly fat, the mentioned fat burning foods will be a great help. Just incorporate them in your diet plan and you’ll be good.
Music: Bouncy Ukulele - guitarsstate licensed from audiojungle https://goo.gl/K3skc7
