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0:00 Intro
0:20 Semiglutide or Ozempic is a GLP-1 agonist.
0:30 GLP-1, glucagon like peptide 1, functions under the category of gastrointestinal incretin hormones that helps you process the foods you eat. It improves insulin sensitivity. Decreases glucagon.
1:30 About 80% of the mechanisms of bariatric surgery is by amplifying the release of incretin hormones.
2:00 There was a 14% loss of body weight in study participants.
2:50 Semiglutide aka Ozempic exerts stress on pancreatic beta cells, with an increased prevalence of pancreatitis and potentially pancreatic cancer.
4:40 GIP and GLP-1 are released after eating to increase insulin secretion from beta cells and prevent post-meal glucose excursions.
5:50 The diminished activity of GIP and GLP-1 is a feature of type-2 diabetes, beta cell insulin resistance, an obesity.
7:10 Exercise increases the release of gastrointestinal incretin hormones.
7:25 Berberine increases gut hormones and changes your microbiome.
7:40 These incretin hormones control the ecosystem of your gut microbiome and can improve function of immune cells around your gut.
8:10 Bifidobacterium can lead to a healthier GI incretin response.
9:00 GABA and L-glycine.
9:45 Protein and fat.
10:30 Polyphenols
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