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**GLP-1 News | May 5 — WHO Backs GLP-1s, Lilly Hits \$6B, CVS Picks Wegovy, and More** Welcome to *The Downsized News*, your trusted source for real updates, honest analysis, and patient-first reporting about GLP-1 medications like Zepbound, Mounjaro, Wegovy, Ozempic, and semaglutide. In this episode, Christopher and Laraine Durham—who’ve lost more than 150 pounds combined using GLP-1s—bring you the latest headlines and why they matter for real people using these medications to treat the disease of obesity. Here’s what we’re covering this week: * **The World Health Organization (WHO)** is officially backing GLP-1s for the treatment of obesity in adults. This is a major turning point—but they also warn that cost and access remain global barriers. We break down what this could mean for the future of coverage and generics. * **CVS Caremark’s Big Move**: Starting July 1, Wegovy becomes the preferred GLP-1 on CVS Caremark’s formularies. That could create new access for some—and new roadblocks for others using Zepbound or Mounjaro. We explain how PBMs work and what this decision really means for patients. * **Eli Lilly’s Q1 2025 Earnings**: Lilly just posted over \$6 billion in GLP-1 sales. Zepbound and Mounjaro are dominating the market—and their oral GLP-1 pill, orforglipron, is showing promising results in trials. We discuss the financials, the future pipeline, and what it means for self-pay patients. * **Novo Nordisk & Telehealth Twist**: In a surprising turn, Novo Nordisk has partnered with Hims & Hers, Ro, and LifeMD—platforms they previously warned against. We explore why they made the deal, how the shortage ruling changed everything, and what this means for access and control. * **Research into GLP-1 Effectiveness**: Illumina and Ovation.io are launching the largest-ever study to understand why some people respond to GLP-1s—and others don’t. This kind of research could unlock personalized obesity treatment in the future. * **GLP-1s and Heart Health**: The American Heart Association is funding seven studies to explore how these medications reduce cardiovascular risk, and why not everyone sees the same benefits. It’s a big step toward more tailored care for people with obesity. * **GLP-1s and Liver Disease**: New clinical trial results show semaglutide could help patients with MASH, a serious liver disease tied to obesity. Wegovy is now under FDA review for this indication. * **Oral Semaglutide for Obesity**: The FDA has accepted Novo Nordisk’s application for a once-daily oral version of Wegovy. A decision is expected in late 2025, and it could be a game-changer for people looking for a non-injectable option. At *The Downsized*, we’re not doctors—we’re patients sharing our experience and the latest information to help you stay informed on your GLP-1 adventure. Always talk to your healthcare provider before starting or changing your treatment. DOWNSIZED WEBSITE: https://thedownsized.org/ DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store JOIN CLUB DOWNSIZED: @thedownsized FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ 00:00 Lilly's $6 Billion GLP-1 Bombshell—and What Comes Next 01:23 WHO Endorses GLP-1s for Obesity 07:56 Eli Lilly's Blockbuster Quarter and Future Innovations 12:21 Novo Nordisk Partners with Telehealth Companies 15:21 Research into GLP-1 Effectiveness 19:20 American Heart Association's GLP-1 Research Grants 23:38 Semaglutide's Potential for Treating Liver Disease 28:08 Conclusion and Wrap-Up
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This Turkey Chili is a hearty, fat-burning meal that delivers serious flavor and nourishment in every bite! Lean ground turkey is packed with high-quality protein to keep you satisfied and support muscle tone, while black beans and kidney beans add fiber to aid digestion and help balance blood sugar. Bell peppers, onions, zucchini, and garlic load this dish with antioxidants, vitamins, and natural detox support. Spices like chili powder, cumin, and smoked paprika not only boost metabolism but also create that cozy, crave-worthy chili flavor. A touch of olive oil brings in healthy fats, while lime juice adds a fresh burst that helps with digestion. Topped with creamy avocado or a dollop of Greek yogurt, this chili is a clean, comforting bowl that supports your weight loss goals without sacrificing taste. Eat smart. Burn fat. Feel your best. Ingredients: * 1 tablespoon olive oil * 1 medium yellow onion, diced * 1 red bell pepper, diced * 3 garlic cloves, minced * 1 pound lean ground turkey * 2 tablespoons tomato paste * 1 tablespoon chili powder * 1 teaspoon ground cumin * 1 teaspoon smoked paprika * ½ teaspoon dried oregano * ½ teaspoon sea salt (adjust to taste) * ¼ teaspoon black pepper * 1 (15-ounce) can diced tomatoes * 1 (15-ounce) can black beans, drained and rinsed * 1 (15-ounce) can kidney beans, drained and rinsed * 1 cup low-sodium chicken broth * 1 cup chopped zucchini (optional, for added fiber) * Juice of ½ lime (optional, for brightness) * Fresh cilantro, chopped (for garnish) * Sliced avocado or Greek yogurt (optional toppings) Preparation: Heat the olive oil in a large pot over medium heat. Add the diced onion and bell pepper, and sauté for about 5 minutes until softened. Stir in the garlic and cook for another minute until fragrant. Add the ground turkey and cook until browned, breaking it up with a spoon as it cooks. Stir in the tomato paste, chili powder, cumin, smoked paprika, oregano, salt, and black pepper. Cook for 2 to 3 minutes to allow the spices to bloom. Add the diced tomatoes, black beans, kidney beans, chicken broth, and zucchini if using. Bring the chili to a simmer, then reduce the heat to low. Cover and let it simmer for 25 to 30 minutes, stirring occasionally. If the chili gets too thick, add a splash of broth or water to reach your desired consistency. Stir in lime juice if using. Taste and adjust seasonings as needed. Serve hot, topped with fresh cilantro, avocado slices, or a dollop of Greek yogurt if desired. Subscribe now and start your healthy journey — one bite at a time! 🍴🔥 🍴 Eat to Lose https://youtube.com/@EattoLose 🥤 Drink to Lose https://youtube.com/@DrinktoLose 🍴🥤 Eat & Drink to Lose https://youtube.com/@EatDrinktoLose ⚠️ Disclaimer All content on Eat to Lose is for informational purposes only. It is not medical advice. Always consult a healthcare professional before making any changes to your diet, lifestyle, or health routine.
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Early morning: 1 fruit of your choice + 5 ALMONDS 5 RASINS WORKOUT TIME WALK 20 MINS OR FAT BURNING WORKOUT Breakfast : 1 KATORI PANEER BHURJI + 1 TOAST + 1 CHAI/ COFFEE ( HONEY / JAGGERY )/ 1 vegetable Sandwich /poha/milk oats / 2 MULTIGRAIN PARATHA WITH CURD Mid-morning: 1 GLASS SATTU DRINK/ 1 GLASS COLD COFFEE Lunch : 1 BOWL VEGETABLE BROWN RICE / 2 CHAPATI + DAAL +ANY SBJI + SALAD Snack TEA / COFFEE + MULTIGRA IN BISCUIT / 1 glass buttermilk/ ANY SHAKE OF CHOICE WITH OUT SUGAR Dinner : 1 bowl vegetable dalia PULAO / 2 besan chilla with chutney/ 1 BOWL BOILED SWEET POTATO / 1.5 KATORI DAAL + VEGETABLES + 0.5 KATORTI BROWN RICE / Post Dinner : 1 glass warm low-fat milk HEALTHY RECIPES LINK BELOW Brown rice recipe https://youtu.be/HUTvV6Fkeh4 FAT BURNING WORKOUT || FAT BURNING EXERCISES: https://www.youtube.com/playlist?list=PLAeyJIEEFYcgKlOYdJV3aC0hSZYqbEfuh REDUCE BREAST SIZE||BURN CHEST AND ARM PIT FAT||JUST 3 EASY MOVES in 7 days https://youtu.be/adiZ3GWejIU Reduce Breast Size | 7 Day Challenge |Get Rid of Armpit Fat | Chest Fat at home || Home Workout https://youtu.be/cWXGoa4u7LU HOW TO REDUCE BREAST SIZE AT HOME || CHEST WORKOUT || JUST 1 MIN DAILY #weightloss #homeworkout #reducebreast #workoutforwomen #healthandfitnesstips GET RID OF THIGH FAT BY JUST 1 MIN DAILY || GET RID OF INNER THIGH FAT IN JUST 1 MIN DAILY https://youtu.be/AmEqtGwcqe0 JUST 1 MINUTE DAILY EXERCISE FOR IDEAL WAIST || GET FLAT BELLY IN JUST 1 MIN DAILY https://youtu.be/qHS4U56f5mA Lose fat from love handles | Sides fat | Obliques fat https://youtu.be/0aUFOnJB1XQ HOW TO LOSE THIGH FAT FAST || SIMPLE MOVES TO LOSE INNER THIGH FAT https://youtu.be/lV8VwSnHucg REDUCE SIDE FAT & Get FLAT TUMMY in 1 Minute || Flat Abs in 1 Week Repeat Daily https://youtu.be/r9MYVk0_Q04 5 EXERCISES WOMEN SHOULD DO DAILY || 5 FAT BURNING MOVES || WEIGHT LOSS EXERCISES https://youtu.be/dekpR4W-hu8 5 MINUTE FAT BURNING WORKOUT || FULL BODY WORKOUT TO LOSE WEIGHT FAST https://youtu.be/BU-QOtZvb8w LOSE THIGH FAT IN 1 MINUTE || 3 SIMPLE EXERCISE OF SLIM LEGS|| REPEAT DAILY https://youtu.be/cn7gmryv0WI FAT BURNER Moves||LOWER BACK , HANDS & SLIMMER WAIST WORKOUT | IN 1 WEEK REPEAT DAILY https://youtu.be/dz15BZUUmZA Weightloss Diet PLANS || INDIAN VEGETARIAN DIET PLAN TO LOSE WEIGHT: https://www.youtube.com/playlist?list=PLAeyJIEEFYciMszXHDW1aFIzonhnvRCRY Workout Plan in Hindi & English || Weight Loss Plan: https://www.youtube.com/playlist?list=PLAeyJIEEFYcgIMgwCqviIV_OzB-0aEA5u
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