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Learn about the design of a trail-blazing Randomized Controlled Trial (RCT) that will explore the physiology and biology of brain energy metabolism, while also informing clinical applications of ketogenic therapy as an adjunctive treatment option for patients with bipolar and schizophrenia spectrum disorders. RCTs are considered the gold standard when looking at the efficacy and safety of new treatment options. This type of research is necessary to understand whether ketogenic therapy should be offered as a first-line treatment option, as well as what types of strategies could increase accessibility of this intervention in the future. Dr. Bret Scher interviews principal investigators Dost Öngür, MD, PhD, and Dr. Virginie-Anne Chouinard, MD, about the details of this trial at McLean Hospital, a top-rated, Harvard-affiliated psychiatric hospital.
Learn more about the impressive design of this trial which includes a multidisciplinary approach to clinical care, gathering a variety of data to inform understanding of underlying brain energy mechanisms (including MRIs and metabolic markers), and an “open-label” approach that will allow the control group to opt into ketogenic therapy at the end of the first trial phase if desired.
Dr. Dost Öngür
William P. and Henry B. Test Professor of Psychiatry, Chief of the Division of Psychotic Disorders, & Director of the Schizophrenia and Bipolar Disorder Research Program at McLean Hospital
https://www.mcleanhospital.org/profile/dost-ongur
Dr. Virginie-Anne Chouinard,
Staff psychiatrist and Director of Research at McLean OnTrack™ & Instructor in Psychiatry at Harvard Medical School.
https://www.mcleanhospital.org/profile/virginie-anne-chouinard
Press release about the trial:
https://www.prnewswire.com/news-releases/mclean-hospital-launches-clinical-trial-of-ketogenic-therapy-for-bipolar-disorder-302062402.html
For information on enrolling:
https://clinicaltrials.gov/study/NCT06221852
Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.
Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/
About us:
Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
Timestamps
0:00 Introduction
2:03 Interest leading up to a keto for bipolar study
5:36 Brain energy metabolism and bipolar
7:44 Patient population for the new Harvard study
8:46 About the study
9:21 Dietary studies vs pharmacologic studies
11:55 The different interventions in the keto for bipolar study
14:42 What researchers will be looking at during the clinical trial
17:20 Balancing mechanism and clinical impact in research
19:21 Impact of the clinical trial
21:54 Working with a clinician for ketogenic therapy
25:30 Conclusion
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Welcome to the third Prep Series Episode! I am posting EVERY OTHER DAY up until show day, so turn on post notifications and subscribe! Next episode is two legendary guests!
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Shark Tank India has been a platform for entrepreneurs to showcase their innovative products and receive funding from a panel of investors. In a recent episode, several breakthrough keto products caught the attention of the investors and viewers alike. The keto diet has been gaining popularity for its potential health benefits, including weight loss and improved energy levels. Let’s take a closer look at some of the keto products that made a splash on Shark Tank India.
Revolutionary Keto Snacks
One of the keto products that impressed the investors on Shark Tank India was a line of revolutionary keto snacks. These snacks were not only low in carbohydrates but also high in healthy fats and protein, making them the perfect on-the-go option for those following a keto diet. The entrepreneurs behind the product showcased the variety of flavors available, from spicy jalapeno to savory garlic parmesan, and the investors were impressed with the taste and texture of the snacks. With the increasing demand for keto-friendly snacks, this product has the potential to revolutionize the snack industry.
The entrepreneurs also highlighted the benefits of their keto snacks, including increased satiety and sustained energy levels. The investors were intrigued by the market potential of the product, especially with the rise in the number of people adopting a keto lifestyle. With the right marketing and distribution strategy, this product could become a game-changer in the keto market.
Overall, the investors were impressed with the innovative approach to keto snacks and saw potential for significant growth and profitability. By addressing the growing demand for convenient and healthy keto-friendly options, the entrepreneurs behind this product could see success in the competitive snack market.
Keto Meal Replacement Shakes
Another keto product that caught the attention of the investors on Shark Tank India was a line of keto meal replacement shakes. These shakes were designed to provide a convenient and nutritious option for those following a keto diet, offering a balanced blend of fats, protein, and fiber. The entrepreneurs behind the product emphasized the importance of using high-quality ingredients and ensuring that the shakes were free from artificial flavors and sweeteners.
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The investors were impressed with the taste and nutritional value of the keto meal replacement shakes, noting that they could be a valuable tool for those looking to maintain a ketogenic lifestyle. With the convenience of a ready-to-drink shake, customers could easily incorporate these shakes into their daily routine, whether as a quick breakfast option or a post-workout fuel source.
The entrepreneurs highlighted the potential for customization, allowing customers to tailor the shakes to their preferences by adding fresh fruits or nut butter. This flexibility appealed to the investors, who saw an opportunity to expand the product line and reach a wider audience of health-conscious consumers.
Keto Baking Mixes
One of the standout keto products on Shark Tank India was a range of keto baking mixes that offered a convenient way to enjoy the flavors of traditional baked goods without the guilt of high carbohydrates. The entrepreneurs behind the product showcased the variety of mixes available, from chocolate chip cookies to cinnamon swirl bread, all made with keto-friendly ingredients like almond flour and erythritol.
The investors were impressed with the taste and texture of the baked goods made from the keto baking mixes, noting that they rivalled traditional recipes in flavor and satisfaction. By providing an easy way for consumers to indulge in their favorite treats while staying true to their keto lifestyle, this product has the potential to revolutionize the baking industry.
The entrepreneurs emphasized the simplicity of using the baking mixes, making it accessible for even novice bakers to create delicious keto-friendly treats at home. With the growing trend of home baking and the increasing demand for keto products, this product has the potential to tap into a lucrative market and attract a loyal customer base.
Keto Supplements
Another innovative keto product that made waves on Shark Tank India was a line of keto supplements designed to support the needs of those following a ketogenic diet. The entrepreneurs behind the product highlighted the importance of maintaining proper nutrition while on a keto diet, including the need for essential vitamins and minerals that may be lacking in a low-carb eating plan.
The investors were impressed with the science-backed approach to the keto supplements, which included ingredients like MCT oil and electrolytes to support energy levels and hydration. By addressing common challenges faced by those on a keto diet, such as fatigue and muscle cramps, this product has the potential to enhance the overall experience of following a ketogenic lifestyle.
The entrepreneurs also emphasized the quality and purity of their keto supplements, ensuring that they were free from fillers and additives commonly found in similar products on the market. With a focus on transparency and efficacy, this product has the potential to stand out in a crowded supplement industry and gain a loyal following among keto enthusiasts.
Overall, the investors saw promise in the keto supplements as a valuable addition to the keto market, providing essential support for those looking to optimize their health and wellness while following a low-carb eating plan.
Conclusion
Shark Tank India showcased a range of breakthrough keto products that have the potential to revolutionize the health and wellness industry. From revolutionary keto snacks to keto meal replacement shakes, these products offer convenient and nutritious options for those following a ketogenic lifestyle. With a focus on quality ingredients and innovative solutions, the entrepreneurs behind these products have the opportunity to make a significant impact in the market and attract a loyal customer base. As the keto diet continues to gain popularity, these products have the potential to become staple items for those looking to maintain a healthy and sustainable eating plan.
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GLP-1 receptor agonists like Ozempic and Wegovy aren’t just about curbing hunger while eating—they change how we feel about food before we even take a bite. Research reveals that these drugs increase satiation during the pre-ingestion phase, making us less likely to crave food when we see it. Discover how this neural mechanism can be a game-changer for weight loss.
Watch the full video here: https://www.youtube.com/watch?v=Lhx8hCj71fk
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My #1 FAVORITE Kettlebell Fat Loss Workout 50 Rep Fat Burner | Coach MANdler
~THE WORKOUT~
0:00 - Intro
1:36 - Goblet Pause Squat to Double Hand Swing (5 x 1 squat 👉 5 swings)
2:59 - Goblet Squat (5 reps)
3:13 - Goblet Reverse Lunge (5 reps/leg)
3:36 - Double Hand Swing (5 reps)
3:47 - Deadlift (5 reps)
[Perform 3 Rounds - Rest 2-3 min. b/w each]
***Weight Used: 71 lbs.***
If you’re a busy dude over 30, you need a different approach to burning fat and reviving your anabolic hormones to look good, feel good, and f... good as you age. That’s why I upload new videos every Monday, Wednesday, and Friday on this fitness channel to give you kettlebell beginner and advanced workout videos, including kettlebell fat loss routine, kettlebell training for strength, kettlebell HIIT workouts, etc. I will also share helpful tips and routines that you can do at home or in the gym using dumbbells, barbells, bands, body weight, and other strongman implements. These are designed to achieve maximum muscle development, burn fat for hours, increase core strength and ultimately help you move more explosively WITHOUT experiencing aches and pains from inflammation and overtraining. Best of all, these workouts typically only take 10 minutes or less, so you can get fast & dramatic results that help you look good naked and perform like a BEAST...without dedicating your life to fitness. Follow my videos if you want to look good, feel good, and f... good in under 10 mins a day.
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