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presents episode 2413 | DR BEN BIKMAN w/ Digital Social Hour: Sean Kelly
GLP-1 receptor agonists…
-GLP-1 hormone we all make from small intestine
-stimulated by certain carbs, proteins, fats
-also stimulated by yerba mate tea & allulose
When high, GLP-1 inhibits glucagon [tries to push glucose up]
-helps blood sugar come under control
-induces a sense of satiety by really slowing
down the intestines
GLP-1 receptor agonists…
When first used, it was at a low dose
-primary effect at that time was to inhibit glucogan
-so, used as anti-diabetic med to control blood sugar
-noticed that those on drug for diabetes tended to eat less
New GLP-1 drugs are simply higher doses
-effect: 1. lowers blood sugar
2. really, really slows down intestines
Example: eat lunch, food stays in stomach
4 to 5 hours, into and through intestines
-with drug: food sits in stomach up to 24 hours
-it putrieies in stomach; may freeze intestines
Paper in NEJM: for every 10 pounds weight loss on these drugs:
-6 pounds is fat loss, but: 4 pounds is lean mass LOST
40% of loss is from muscle & bone!
Example: middle age woman, trouble making muscle & bone…
overweight, to takes drug for 24 months…
then drops off the drug Because Tired of Feeling Sick
-result: all weight comes back immediately
-returns to original weight
In older adults: drug helps you lose 40% muscle mass & bone…
-get off drug: fat mass returns Easily, but Not Muscle nor Bone
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original video: https://youtu.be/5HSgBkCMlXo?si=8RRT9CfeCDajC0HM
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Let’s talk weight loss shots — Ozempic, Wegovy, Mounjaro… they’re powerful tools, but they’re not magic potions. 💉✨ These medications help shed pounds, but without movement, you risk losing muscle instead of fat. That’s how people end up smaller but flabby… and we’re not doing that in this season. 😏💅 You deserve to feel strong, toned, and Summer Fine, not just lighter. 👚: Yes, that’s pink spandex. 🏋🏽♀️: Yes, we’re working out. 🧠: And yes, we’re staying educated. Stay cute. Stay fit. Stay informed. — Dr. Sherika 💖 #SummerFine #DrSherikaApproved #WeightLossJourney #OzempicTips #Wegovy #Mounjaro #BodyGoals #NotJustSkinny #HealthIsWealth #FitnessAndPharma #FlabFreeZone #PinkSpandexEnergy
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Thanks for watching! [CREDITS] TTS from Google Cloud Text-To-Speech API Music by Kevin Macleod Parkour Isle created by _Artem_ on Planet Minecraft (www.planetminecraft.com/project/parkour-isle/) Programmed using Python 3.12.8, PRAW, moviepy, and many other libraries Question by u/Waste-Banana6539 (www.reddit.com/r/askreddit/comments/1jeuqqv) Comment 1 by u/Baconated-grapefruit

