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In this episode, my guest is Dr. Zachary Knight, Ph.D., a professor of physiology at the University of California, San Francisco (UCSF), and Howard Hughes Medical Institute (HHMI) investigator. We discuss how the brain controls our sense of hunger, satiety, and thirst. He explains how dopamine levels impact our cravings and eating behavior (amount, food choices, etc) and how we develop and can change our food preferences and adjust how much we need to eat to feel satisfied.   We discuss factors that have led to the recent rise in obesity, such as interactions between our genes and the environment and the role of processed foods and food combinations. We also discuss the new class of medications developed for the treatment of obesity and diabetes, including the GLP-1 agonists semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro). We discuss how these medications work to promote weight loss, the source of their side effects, and the newer compounds soon to overcome some of those side effects, such as muscle loss.   Dr. Knight provides an exceptionally clear explanation for our sense of hunger, thirst, and food cravings that translates to practical knowledge to help listeners better understand their relationship to food, food choices, and meal size to improve their diet and overall health. Access the full show notes, including referenced articles, books, people mentioned, and additional resources: https://www.hubermanlab.com/episode/dr-zachary-knight-the-science-of-hunger-medications-to-combat-obesity Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Eight Sleep: https://eightsleep.com/huberman Waking Up: https://wakingup.com/huberman LMNT: https://drinklmnt.com/huberman Huberman Lab Social & Website Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter Dr. Zachary Knight UCSF academic profile: https://profiles.ucsf.edu/zachary.knight HHMI profile: https://www.hhmi.org/scientists/zachary-knight Publications: https://knightlab.ucsf.edu/publications Lab website: https://knightlab.ucsf.edu X: https://x.com/zaknight Instagram: https://www.instagram.com/zknightsf LinkedIn: https://www.linkedin.com/in/zachary-knight-29a37977 Timestamps 00:00:00 Dr. Zachary Knight 00:02:38 Sponsors: BetterHelp, Helix Sleep & Waking Up 00:07:07 Hunger & Timescales 00:11:28 Body Fat, Leptin, Hunger 00:17:51 Leptin Resistance & Obesity 00:20:52 Hunger, Food Foraging & Feeding Behaviors, AgRP Neurons 00:30:26 Sponsor: AG1 00:32:15 Body Weight & Obesity, Genes & POMC Neurons 00:39:54 Obesity, Genetics & Environmental Factors 00:46:05 Whole Foods, Ultra-Processed Foods & Palatability 00:49:32 Increasing Whole Food Consumption, Sensory Specific Satiety & Learning 00:58:55 Calories vs. Macronutrients, Protein & Salt 01:02:23 Sponsor: LMNT 01:03:58 Challenges of Weight Loss: Hunger & Energy Expenditure 01:09:50 GLP-1 Drug Development, Semaglutide, Ozempic, Wegovy 01:19:03 GLP-1 Drugs: Muscle Loss, Appetite Reduction, Nausea 01:23:24 Pharmacologic & Physiologic Effects; GLP-1 Drugs, Additional Positive Effects 01:30:14 GLP-1-Plus Development, Tirzepatide, Mounjaro, AMG 133 01:34:49 Alpha-MSH & Pharmacology 01:40:41 Dopamine, Eating & Context 01:46:01 Dopamine & Learning, Water Content & Food 01:53:23 Salt, Water & Thirst 02:03:27 Hunger vs. Thirst 02:05:46 Dieting, Nutrition & Mindset 02:09:39 Tools: Improving Diet & Limiting Food Intake 02:14:15 Anti-Obesity Drug Development 02:17:03 Zero-Cost Support, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter #HubermanLab #Health #Obesity Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com Disclaimer: https://www.hubermanlab.com/disclaimer

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Running is consider one of the best way to burn fat but knowing the science behind fat burn can help you achieve your belly fat loss or fat burn goal easily. How much fat running can burn, depends on factors like metabolic rate, age, height, and weight. Running burns a mix of fat and carbohydrates, with the ratio depending on heart rate. To effectively burn fat, it's important to run at a moderate intensity for a longer duration, while also focusing on maintaining a calorie deficit through diet. Queries answered in this video 1) Can running help lose bellyfat? 2) how much fat can we burn while running? 3) Is running good for fatloss? 4) can running help you lose fat? 5) will running lose belly fat? 6) How body burn fat 7)does running burn belly fat? 8) how to lose weight by running? 9) marathon training tips 10) will running help lose belly fat 11) Walking better than running for weight loss? 12) running on treadmill for weight loss? 13) is running best way to loose belly fat? 14) weight loss running workout Video includes 1) basic running tips for beginners 2) how to start running for beginners? 3) best cardio for fat loss 4) fat kam kaise kare? 5) best fat burner 6) does running increase height? 7) best cardio workout to burn belly fat 8) does running burn belly fat? 9) easiest way to lose fat 10) does running help you lose weight? 11) how to increase metabolism to lose weight? 12) how your body burns fat? 13) running fat loss 14) marathon training tips belly fat removal best cardio for fat loss running tips for beginners fat kaise badhaye best fat burner how to increase metabolism to lose weight how to start running for beginners running tips for beginners does running increase height running for fat loss running fat loss running for beginners how to increase metabolism weight loss kaise kare tips to increase height best exercise for height increase calories deficit means does running burn belly fat marathon training tips basic running tips for beginners belly fat removal best diet to lose belly fat best exercises to increase height fat burning medicine fat kaise badhae fat kaise kam karen fat loss running weight loss by running will running help lose belly fat belly fat loss medicine best cardio for fat loss best cardio workout to burn belly fat fat burner fat kaise loss karen fat runner how fat burns in the body how to easily lose weight how to increase fat in body how to lose belly fat without exercise (science based method) how to lose weight easily how to lose your belly fat how to start running how to start running for weight loss how your body burns fat increase metabolism lose weight is running good for fat loss lose weight easily running exercises to lose weight running for beginners weight loss running training for beginners start running for beginners tips to run faster and longer weight according to height and age weight loss and height increase exercise weight loss tips where do you lose fat first #Running #Runner #RunMotivation #RunnersOfYouTube #MorningRun #EveningRun #RunForLife #RunChallenge #RunDaily #RunToInspire #RunStrong #RunningCommunity #RunnersWorld #CardioRun #RunTraining #RunTips #LongRun #TrailRunning #RoadRunning #MarathonTraining #RunningVlog #RunningJourney #StartRunning #5kTraining #FatBurn #BurnCalories #FatBurningWorkout #LoseFat #BurnThatFat #FatLossTips #HIITforFatLoss #CardioBurn #LoseBellyFat #HomeFatBurn #WeightLossJourney #FatLossMotivation #FatBurnChallenge #WorkoutToBurnFat #FatLossWorkout #SweatItOut #ShredFat #FatLossGoal #MeltFat #BurningFatFast #FitnessMotivation #NeverGiveUp #NoExcuses #DisciplineEqualsFreedom #FitLife #HealthyLifestyle #ConsistencyIsKey #FitnessJourney #MindOverBody #TrainHard #HealthyHabits #FitnessAddict #GrindMode #PushYourLimits #MotivationDaily #JustDoIt #GoalGetter #FitGoals #WellnessJourney #StayFit #YouTubeShorts #FitnessYouTuber #WorkoutVideo #RunningVideo #ShortsFitness #ViralFitness #FitnessContent #FitnessShorts #RunningTips #RunningShorts #FatBurnTips #YouTubeFitness #FitnessInfluencer #FitnessYouTubeIndia #VlogYourRun #CardioOnYouTube #FitnessShortsIndia #ShortsViral #YouTubeFitFam #FitCreator #WeightLoss #CardioWorkout #GetFit #WorkoutRoutine #FitnessTransformation #HomeWorkout #RunningForFatLoss #OutdoorWorkout #FitnessTips #BodyTransformation #FastFatBurn #RunningForBeginners #FitnessLife #RunningGoals #FatBurnRoutine

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In today’s episode, Dr. Tyna and I discuss GLP-1 peptides, their benefits, and the misconceptions surrounding them. Here are my key takeaways that I believe everyone should consider: Personalized Dosing is Key: Dr. Tyna emphasizes the importance of individualized dosing for GLP-1 peptides, noting that a one-size-fits-all approach is ineffective. Factors like weight, metabolic health, age, and lifestyle determine the appropriate dosage, helping to mitigate side effects and enhance therapeutic benefits. It’s a reminder that healthcare should always be tailored to the individual! The Broader Benefits Beyond Weight Loss: While GLP-1s are known for weight loss, Dr. Tyna highlights their potential in areas like neuroinflammation, cardiovascular health, and autoimmune conditions. This shift in focus encourages us to consider the holistic benefits of these peptides for overall health and wellness. I encourage everyone to listen to this episode for a deeper understanding of GLP-1 peptides and their potential impact on health. Dr. Tyna’s insights are invaluable, and I believe they can help many navigate their health journeys more effectively. Bio: With nearly thirty years immersed in the medical field, Dr. Tyna Moore is an expert in holistic regenerative medicine and resilient metabolic health. She is licensed as a Naturopathic Physician and a Chiropractor, drawing on knowledge from both traditional and alternative fields of science and medicine to provide a comprehensive perspective to individuals striving to enhance their health and wellbeing. Dr. Tyna holds degrees from the National College of Natural Medicine, an esteemed naturopathic medical school, and the University of Western States Chiropractic College. Her work is not just about treating symptoms, it’s about understanding and healing root causes to build a robust foundation for long term wellbeing. She is well-known for her fierce and open-minded exploration of the peptide, Semaglutide/Ozempic, as a longevity tool for healing. Dr. Tyna champions medical autonomy and individual accountability, and she is on a mission to help as many people as possible experience the freedom and joy that health brings. Connect with Dr. Tyna Moore: Instagram: @drtyna Website: www.drtyna.com Youtube: DrTynaMoore Ozempic Course: Ozempic Uncovered Course Podcast: https://podcasts.apple.com/us/podcast/the-dr-tyna-show/id1577258582 For 15% OFF your first order at Ilia Use code Just Ingredients at checkout at https://iliabeauty.nhuie7.net/VyEDAJ Looking for more Just Ingredients content? Instagram Stories: @just.ingredients Podcast Instagram: @just.ingredients.podcast Facebook Community: Join our group Discover our non-toxic product line: Shop Just Ingredients Timestamps: 0:00 Intro 0:23 Tyna Moore Bio 1:02 Welcome Tyna Moore 4:06 What Are Peptides and GLP-1's? 7:52 GLP-1 Geeting FDA Approved for Weightloss 13:06 The Important to Individualized Dosing 17:50 These Side Effects Could Indicate Your Dose Is Too High 20:00 Malnutrition From Appetite Suppression 21:34 Myth of Acquiring Gut Paralysis 24:24 Myth of Acquiring Thyroid Cancer 26:48 These Two Groups Have The Highest Risk For Thyroid Cancer 27:34 Myth of Acquiring Breast Cancer 29:08 Muscle Mass Loss Issues 35:13 Ilia Ad 36:25 Reduction In Cravings: Mind and Body 38:34 Can GLP-1's Reduce Suicide Ideation? 40:46 How GLP-1's May Help Depression 43:23 Cycling, Short-Term, and Long-Term Dosing 47:16 Standard Dosing 48:48 Types of GLP-1's 54:54 GLP-1's Are Not a Substitute For Healthy Lifestyles 57:12 GLP-1's Are Perimenopause Women's BFF's 1:01:14 Resources Available 1:02:22 What Is The Best Ingredient In Life?

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The popularity of the ketogenic diet has skyrocketed in recent years, with many people turning to this low-carb, high-fat eating plan to help them lose weight and improve their overall health. One of the challenges of following a keto diet is finding ways to satisfy your sweet tooth without derailing your progress. That’s where Keto Blast Gummies come in. These delicious gummies are specially formulated to help you stay in ketosis while also satisfying your cravings for something sweet.

Keto Blast Gummies: What Are They?

Keto Blast Gummies are a convenient and delicious way to incorporate the benefits of the keto diet into your lifestyle. These gummies are made with a unique blend of ingredients that are designed to support your body’s fat-burning processes and help you stay in ketosis. Each gummy is packed with essential nutrients and natural flavors, making it easy to stick to your keto diet while also enjoying a tasty treat.

One of the key ingredients in Keto Blast Gummies is exogenous ketones, which are known for their ability to increase your body’s ketone levels and promote fat burning. These ketones can help you reach and maintain ketosis more easily, allowing you to experience the benefits of the keto diet more quickly.

In addition to exogenous ketones, Keto Blast Gummies also contain other ingredients that can help support your overall health and well-being. These include vitamins, minerals, and antioxidants that can help boost your immune system, improve your energy levels, and support healthy digestion.

How to Use Keto Blast Gummies

Using Keto Blast Gummies is simple. Just take one or two gummies per day, depending on your individual needs and preferences. These gummies can be taken with or without food, making them a convenient option for anyone following a busy schedule.

For best results, it’s recommended to incorporate Keto Blast Gummies into a healthy ketogenic diet and regular exercise routine. By combining these gummies with a balanced diet and active lifestyle, you can maximize your results and reach your weight loss goals more effectively.

It’s important to note that Keto Blast Gummies are not a magic solution for weight loss. While they can support your keto diet efforts, they work best when used in conjunction with a healthy lifestyle. Remember to stay hydrated, get plenty of sleep, and listen to your body’s signals while using these gummies.

Benefits of Keto Blast Gummies

There are many potential benefits to incorporating Keto Blast Gummies into your daily routine. These gummies can help you:

– Stay in ketosis more easily
– Support your body’s fat-burning processes
– Improve your energy levels
– Boost your immune system
– Enhance your overall well-being

By enjoying these delicious gummies regularly, you can experience these benefits and more while sticking to your keto diet and achieving your weight loss goals.

Are Keto Blast Gummies Right for You?

If you’re looking for a tasty and convenient way to support your keto diet and enjoy a sweet treat without the guilt, then Keto Blast Gummies could be a great option for you. These gummies are designed to help you stay in ketosis, boost your energy levels, and support your overall health, making them a valuable addition to your daily routine.

Before incorporating any new supplement into your diet, it’s always a good idea to consult with your healthcare provider to ensure that it’s safe and appropriate for you. By discussing your goals and needs with a professional, you can determine whether Keto Blast Gummies are the right fit for you and start enjoying the benefits of these delicious gummies.

Summary and FAQ

In conclusion, Keto Blast Gummies are a convenient and tasty way to support your keto diet and reach your weight loss goals. These gummies are made with high-quality ingredients that are designed to help you stay in ketosis, boost your energy levels, and support your overall well-being. By incorporating Keto Blast Gummies into your daily routine and following a healthy lifestyle, you can enjoy the benefits of the keto diet more effectively and satisfy your sweet cravings without compromising your progress.

If you have any questions about Keto Blast Gummies or how to incorporate them into your diet, check out the official website for more information and reviews from satisfied customers. With the support of Keto Blast Gummies, you can take your keto diet to the next level and experience the transformative benefits of this popular eating plan.

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