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Cialis (tadalafil) and Viagra (sildenafil) are both medications used to treat erectile dysfunction (ED), but they have several differences in terms of how they work, how long they last, and their potential side effects. Here's a comparison: 1. Active Ingredient Cialis: Contains tadalafil. Viagra: Contains sildenafil. 2. How Long They Last Cialis: Known for its longer duration of action. It can last up to 36 hours after taking the pill, which is why it is often called the "weekend pill." This longer window allows more spontaneity. Viagra: Lasts for about 4 to 6 hours after taking it. It is more short-acting compared to Cialis. 3. Time to Start Working Cialis: Takes about 30 minutes to 2 hours to start working, though some men may notice effects within 30 minutes. Viagra: Typically starts working within 30 to 60 minutes after taking the pill. It’s recommended to take Viagra about 1 hour before sexual activity. 4. Food Interactions Cialis: Can be taken with or without food. Food does not significantly affect how Cialis works. Viagra: It is best taken on an empty stomach. Eating a high-fat meal before taking Viagra can delay its onset of action. 5. Daily vs. On-Demand Use Cialis: Can be taken daily in a lower dose (2.5 mg or 5 mg) for those who prefer spontaneous sexual activity without planning. It can also be taken on demand in a higher dose (10 mg or 20 mg). Viagra: Is usually taken on an as-needed basis, about 30-60 minutes before sexual activity. It is not typically used for daily dosing. 6. Dosage Cialis: Common dosages are 2.5 mg, 5 mg, 10 mg, and 20 mg. Viagra: Common dosages are 25 mg, 50 mg, and 100 mg. 7. Side Effects Both medications have similar side effects, though some men may respond differently depending on the drug: Cialis: Common side effects include headache, indigestion, back pain, muscle aches, and flushing. Back pain and muscle aches are more common with Cialis. Viagra: Common side effects include headache, flushing, upset stomach, nasal congestion, and dizziness. Vision changes (like a blue tinge to vision) are more commonly associated with Viagra. 8. Uses Beyond Erectile Dysfunction Cialis: In addition to treating ED, Cialis is also approved to treat benign prostatic hyperplasia (BPH), which is an enlarged prostate. Viagra: Viagra is primarily used to treat ED, but it is also sometimes used to treat pulmonary arterial hypertension (under the brand name Revatio). 9. Cost Cialis: Typically more expensive than Viagra, especially the daily version. Viagra: Generic versions (sildenafil) are available, making it more affordable than Cialis. 10. Flexibility Cialis: Offers more flexibility due to its long duration, making it a good option for men who prefer not to time their medication with sexual activity. Viagra: Works well for men who are comfortable taking a pill shortly before sex and don’t need the long-lasting effects of Cialis.

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